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Drug Treatment Plan Should Consider Risks and Benefits of Individual Patients
Drugs are helpful in treating osteoporosis, but figuring out which drug to prescribe means evaluating the pluses and minuses of each option for each patient, according to new recommendations from The American College of Physicians.
As people get older their bones become less dense and more vulnerable to fracture. In its severe form, this condition is known as osteoporosis. Osteoporosis is particularly common in women after menopause, though men get it too. WebMD
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Major lifestyle changes can help improve levels of an enzyme called telomerase that controls cell aging, say California researchers.
Telomerase repairs and lengthens telomeres, which are DNA-protein complexes at the end of chromosomes that directly affect how quickly cells age. As telomeres become shorter and their structural integrity weakens, cells age and die more quickly, according to background information in a University of California, Irvine, new release. Shortening of telomeres is emerging as a marker of disease risk and premature death in many types of cancer, including prostate, lung, breast and colorectal cancers.
In this study, Dr. Dean Ornish, a professor of medicine at the Preventive Medicine Research Institute in Sausalito, Calif., and his colleagues at the University of California, San Francisco, asked 30 men diagnosed with low-risk prostate cancer to make significant lifestyle changes. Your Total Health
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DRINKING can be good for your heart. But you have to be a lazy smoker with an aversion to fruit and vegetables to reap the full benefits.
In possibly the most unfair medical finding this year, Britain's leading researcher on the link between health and behaviour, the Australian expatriate Michael Marmot, found that smokers with the worst diets and poorest exercise habits could consume as many as 14 standard drinks a week - the threshold of what is considered harmful under proposed Australian guidelines - and still lower their risk of having a heart attack, stroke or other form of cardiovascular disease. Life & Style
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Motion sensors similar to those developed for video games like Nintendo Wii may help stroke patients relearn simple tasks, researchers say.
A UK team is assessing such technology to see if it can be used to monitor improvements in upper body movements in patients undergoing physiotherapy.
The Oxford University team hope it will allow patients to see their progress and motivate them to keep exercising.
Clinical trials of the equipment are being planned.
It is hoped the motion sensors will also help physiotherapists assess the range of movement a patient has and help them tailor exercises accordingly. BBC News
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Scans could improve docs' ability to diagnose location of defects, study says
Soft-tissue defects that contribute to hearing loss in children can be detected using MRI, say U.S. researchers who analyzed the medical records of hundreds of children diagnosed with sensorineural (related to sensory nerves) hearing loss.
Radiography, including computed tomography (CT) and X-rays, is often used to look for bone structures problems in children with hearing loss. However, defects in the soft tissue within the bones may also cause hearing loss. USA Today
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 Higher levels of urinary Bisphenol A (BPA), a chemical compound commonly used in plastic packaging for food and beverages, is associated with cardiovascular disease, type 2 diabetes and liver-enzyme abnormalities, according to a study in the September 17 issue of JAMA. This study is being released early to coincide with a Food and Drug Administration (FDA) hearing on BPA.
BPA is one of the world's highest production–volume chemicals, with more than two million metric tons produced worldwide in 2003 and annual increase in demand of 6 percent to 10 percent annually, according to background information in the article. It is used in plastics in many consumer products. Science Daily
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 Pat’s nursing home, Chatsworth, is a short walk through a neighborhood park, past a gazebo, across player-worn soccer fields. On good-weather days I bike, hauling her laundry in a backpack; folding her clothes helps me feel normal.
Pat has lived here for more than two years, one of 18 residents of a locked-down dementia unit called Chelsea Meadows. Though she is 20 years younger than the others, Alzheimer’s has already done just about everything it will do to her. Except kill her. That will happen here. The hospice calls it “dying in place.” Enter through the double doors, and you are at one end of a bright and airy great room that is half a football field long and does not look it. The space is residence hall, living room, dining room, lounge and kitchen all in one. Columns, arches, recessed bedroom doorways, hanging baskets of silken ivy and planters of crafts-store bougainvillea bring the scale down to size. The New York Time
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 The investigational once-daily oral mammalian target of rapamycin (mTOR) inhibitor RAD001 (with the proposed brand name Afinitor), formerly known as RAD001, significantly prolongs disease-free survival in patients with metastatic renal cell cancer who have stopped responding to targeted therapy, investigators reported here at the 33rd Annual Congress of the European Society of Medical Oncology (ESMO).
Bernard Escudier, MD, with the Institut Gustave Roussy in Villejuif, France, presented results in 410 patients who had been randomized in a 2:1 design to treatment with RAD001 10 mg/d plus best supportive care or placebo plus best supportive care. Medical News Today
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Sex triggered a life-threatening stroke in a healthy 35-year-old Illinois woman, her doctors report.
Sex- and orgasm-triggered strokes in relatively young women and men are rare, but not unheard of. They require a combination of factors and events not unusual in themselves, but which are highly unlikely to occur at the same time.
The 35-year-old woman's symptoms were typical of this unusual kind of "cryptogenic" stroke, says Jose Biller, MD, professor and chair of the neurology department at Loyola University, Chicago.
"This young woman ... while having intercourse had numbness on the left side of her face, slurred speech, and weakness in her left arm," Biller tells WebMD. "When she was transferred to our care six hours after onset, she was completely unable to move her left arm, her face was paralyzed, her speech was garbled, and she was in a state of panic." WebMD
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 Unlike some parents, adult stem cells don't seem to mind when their daughters get a tattoo. In fact, they're willing to pass them along.
Using the molecular equivalent of a tattoo on DNA that adult stem cells (ASC) pass to their "daughter" cells in combination with gene expression profiles, University of Utah researchers have identified two early steps in adult stem cell differentiation—the process that determines whether cells will form muscle, neurons, skin, etc., in people and animals.
The U of U researchers, led by Alejandro Sánchez Alvarado, Ph.D., professor of neurobiology and anatomy, identified 259 genes that help defined the earliest steps in the differentiation of adult stem cells in planarians—tiny flatworms that have the uncanny ability to regenerate cells and may have much to teach about human stem cell biology. Science Daily
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 Hospira (NYSE: HSP), the world leader in generic injectable pharmaceuticals, presented new data showing Retacrit® (epoetin zeta) is an effective treatment for chemotherapy-induced anaemia,1 with an acceptable safety and tolerability profile.2 Results from the Phase III trial were presented at the European Society for Medical Oncology (ESMO) congress.
Retacrit is a biosimilar erythropoietin approved in Europe3 for subcutaneous administration in the treatment of anaemia associated with chemotherapy. Efficacy, safety and tolerability in this indication were evaluated from an open-label Phase III trial involving 216 patients with solid tumours, malignant lymphoma or multiple myeloma who were undergoing chemotherapy. Medical News Today
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Forget the facelift, how about sprucing up the old back?
The American Society of Plastic Surgeons is pitching a new procedure to get rid of skin rolls on your middle and upper back. The group is releasing results of a small study of seven women who had what is being called the "bra-line back lift" between 2001 and 2007.
Seven women underwent the procedure for this study. The average age was 54.
Plastic surgeons went in and sliced out skin tissue, some of it 8 to 10 inches wide. The remaining tissue was reattached.
The scar was conveniently hidden under the women's bra line. The procedure took about an hour, according to researchers. Patients were urged to get up and moving within two weeks, depending on how much pain they were feeling.
The women were followed for nearly two years. Two of them had to have their scars redone within a year of their back lift surgery. Study authors don't say whether the women have since regained the fat. WebMD
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